Pain helps us survive, and yet some people are born without the ability to feel pain, how?
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Transcriptional regulator PRDM12 is essential for human pain perception http://www.nature.com/ng/journal/v47/n7/full/ng.3308.html
“Pain perception has evolved as a warning mechanism to alert organisms to tissue damage and dangerous environments. In humans, however, undesirable, excessive or chronic pain is a common and major societal burden for which available medical treatments are currently suboptimal”
Why do we experience physical pain?
“There’s no doubt about it: Pain sucks. We all hate it — and some people go to immense lengths to try and get rid of chronic pain. And yet, it’s a constant part of human experience. But why do people feel physical pain? How does it even work? And does everybody feel pain the same way?”
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